Panama Canal Cruises 2024 From San Francisco. Lauderdale to los angeles or san francisco, or cruise from either of those two west coast cities to florida. Marvel at the engineering feat of the panama canal, see sloths in costa rica and feel the hairpin bends of big sur.
Find and plan your next cruise from san francisco to the panama canal & central america on cruise critic with a variety of departure dates and popular cruise lines to choose from. You’ll have the chance to see volcanic peaks and mayan ruins, explore.